Ageing skin displays a number of changes that contribute to wrinkles and loss of skin elasticity. Photoageing is the acceleration of this natural ageing process caused by exposure to sunlight and sun beds.
Epigenetics describes the control of a person’s genes by factors other than the sequence of their DNA. It is possible that exposure to sunlight can affect genes by switching them ‘on’ or ‘off’ in the skin.
Adults between the ages of 18-30 or 65 and older who have:
There are also a number of people who may not take part including: sunbed users, smokers, pregnant or breastfeeding women, diabetics, drug users, shift workers, those with a history of keloid scars, users of topical or systemic retinoids or steroids, anyone currently taking anticoagulant medication, anyone who has been tattooed within the last month, anyone with a skin disease or any employees of the study site or sponsor.
Volunteers will be asked to return daily to the clinic for up to twelve days (excluding weekends). They will be asked to complete a short lifestyle questionnaire and to provide a brief medical history.
The study will then commence as follows:
Dermatopharmacology Department, 1st Floor Barnes Building, Salford Royal NHS Foundation Trust